How to Overcome Perfectionism

The Depression Trial That Never Touched the Brain

The Depression Trial That Never Touched the Brain Here is a strange result. Last month, researchers gave an arthritis drug to a group of patients with hard-to-treat depression, and many of them got better. The drug, tocilizumab, does nothing to serotonin, dopamine, or any of the usual suspects. It works on the immune system, quieting […]

The Opioid System Psychiatry Chose to Forget

Iridescent brain render representing neural opioid pathways

There is a system in the brain that regulates social bonding, emotional pain, pleasure, and the will to keep going. It is, by most accounts, one of the most important systems for understanding why people become suicidal. Psychiatry has spent the better part of four decades pretending it doesn’t exist. The endogenous opioid system, the […]

Your Diagnosis Might Be a Zip Code, Not a Disease

The labels psychiatry assigns to mental illness are useful. They give patients language for what they’re feeling, give clinicians a shared vocabulary, give insurance companies something to reimburse. But they aren’t exact the way a CT scan is exact. The Diagnostic and Statistical Manual, the field’s bible since 1952, carves the mind into categories based […]

The Most Dangerous Drug in Psychedelic Medicine Just Got an FDA Green Light

In the Bwiti tradition of Gabon, ibogaine is not a drug. It is an initiation. Young members of the community consume the bark of the Tabernanthe iboga root and spend days in a visionary state that the Bwiti consider a kind of death and rebirth. Western pharmacology has spent sixty years trying to figure out […]

The FDA Just Fast-Tracked Psychedelics. Here’s What That Actually Means.

For most of modern psychiatry’s existence, clinicians have been handing patients the same basic categories of medication (SSRIs, SNRIs, benzodiazepines, antipsychotics) and hoping one sticks. Try a pill, wait six weeks, feel weird, try another, wait six more weeks, feel different-weird. It helps a lot of people, but for treatment-resistant depression, the kind that doesn’t […]

Why TMS Works for Some People But Not for Others

tms therapy work

Transcranial Magnetic Stimulation (TMS) has been hailed as a game-changing treatment for depression, particularly for those who haven’t responded to medication. It’s non-invasive, doesn’t require drugs, and has been FDA-approved for conditions like major depressive disorder (MDD), OCD, and anxiety. But here’s the catch—while many people experience significant relief, others don’t see much improvement at […]

Who Qualifies for TMS Therapy? Understanding the Criteria for OCD Patients

TMS Therapy for OCD

Obsessive-Compulsive Disorder (OCD) can be a debilitating condition, interfering with daily life, relationships, and overall well-being. While traditional treatments like medication and therapy work for many individuals, some struggle to find relief. This is where Transcranial Magnetic Stimulation (TMS) therapy comes in—a non-invasive, FDA-approved treatment offering new hope for those with treatment-resistant OCD. But who […]

When Should You Consider TMS Therapy?

TMS Therapy

Transcranial Magnetic Stimulation (TMS) therapy is a cutting-edge treatment that has gained significant attention in recent years for its potential to help individuals struggling with mental health disorders. But when exactly should you consider TMS therapy? Let’s dive into what TMS is, how it works, and the scenarios in which it might be the right […]

The Role of Diet in Fighting Depression: What Science Says

diet

In today’s fast-paced world, depression affects millions of people, cutting across all age groups and demographics. While therapy and medication are essential for many individuals, emerging research has highlighted the powerful role of nutrition in managing and even alleviating symptoms of depression. A growing body of evidence suggests that the food we consume plays a […]

Natural Ways to Manage Depression: Lifestyle Changes That Make a Difference

Manage Depression

Depression can feel overwhelming, casting a shadow over daily life. While medical treatments such as therapy and medication are vital for many, incorporating natural lifestyle changes can play a significant role in managing depression. By focusing on holistic habits, individuals can support their mental health and create a foundation for long-term wellness. Here are practical, […]